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Antidepressant may help the workings of anticancer drug used in leukemia By Dr Ananya Mandal.

Retinoids are a course of chemical compounds related chemically to supplement A. ATRA is already used successfully to take care of a rare type of acute myeloid leukemia , but up until now, is not effective against other types of the disease. ATRA functions by encouraging leukemia cells to mature and die naturally, but the experts say that the reason why many AML patients do not react to the treatment is basically because the genes that ATRA normally attacks are powered down by an enzyme called LSD1. The scientists found that using TCP to block this ‘off switch’ could reactivate these genes, making the cancers cells susceptible to ATRA. We’ve now found a way to harness these effective drugs to treat far more common types of leukaemia. Until now, it’s been a mystery why the other styles of AML don’t react to this drug. Continue reading

Related StoriesEstrogen-like drug may not be good for women with Alzheimer&39.

The experts at the Geriatric Mental Health Program at the Center for Addiction and Mental Wellness say the results suggest a fresh direction in medications for psychotic disorders related to dementia in older people. Related StoriesEstrogen-like drug may not be good for women with Alzheimer's dementiaHealth Education England launches Dementia Core Skills Education and Schooling FrameworkBU researcher gets prestigious fellowship to release new project for those who have dementiaThe researchers say they did not expect an antidepressant could have antipsychotic properties but also state that antipsychotics stay the first-range treatment for Alzheimer’s-related psychosis and more studies are needed to confirm their findings. Continue reading

American diners prefer meals that offer the many nutrition for the calories When eating out.

In fact, according to a new Guiding Stars survey, 65 % of Us citizens prefer to see nutritional info through either the Diet Facts Panel or a good-better-best rating system over just calorie count . Related StoriesWWP's Physical Health and fitness System hosts wounded veterans for fitness and nourishment seminarNew BU research reveals difficulties of providing good diet, hydration in people who have dementia in caution homesProper iodine diet necessary during pregnancyAn Easy-to-Use Restaurant Menu Nourishment Profiling System When you consider that, based on the survey, over one-quarter of Americans found the Diet Facts Panel exhausting to learn, many diners clearly look for a far more simplified tool to greatly help them easily identify the meals offering the most nutrition for the calories. Continue reading

By innoculating monkeys with SIV.

Studying the monkeys after exposure, researchers uncovered the websites of transmission and an instant spread of the virus to encircling lymphoid tissues. Sites of an infection included soft cells in the mouth Likely, esophagus and tonsils. Related StoriesNew vaccine candidate shows great promise at fighting respiratory syncytial virusMillions even more bird species killed by West Nile virus than previously thoughtStudy provides novel insight in to the development of hepatitis A virus and how it spreads to humansFurther study of the digestive system showed that SIV was not present in tissues below the esophagus until four days post-infection, indicating that the stomach acids most likely avoided the virus from entering through the abdomen or intestines. ‘It is very clear from our research that the oral and esophageal mucosa and the tonsils are likely to be the most crucial sites of viral entry,’ Dr. Continue reading

CASIs ENMD-2076 gets FDA Orphan Medication designation for HCC treatment CASI Pharmaceuticals.

Dr. Ken Ren, Chief Executive Officer of CASI, commented, We are happy with the Orphan Medication designation since it confirms our belief in the versatility of ENMD-2076 as a promising treatment for HCC, and for other tumor types that we are evaluating in the clinic currently. Orphan drug status enhances the commercial value of ENMD-2076 to take care of HCC also, a disease which is tough to take care of. We are finalizing our next steps for ENMD-2076 in HCC and/or in fibrolamellar carcinoma, a subset of HCC and for which there is no treatment available and appearance forward to advancing our general development plan for ENMD-2076. Continue reading

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