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Study topics will undergo rigorous protection screening before they are enrolled in the trial, and you will be carefully monitored every two to a month with efficacy and basic safety assessments. We are thrilled that the researchers at the Seaver Autism Center are undertaking this pilot research to evaluate a feasible treatment for SHANK3 deficiency, which may also help everyone with ASD, said Geraldine Bliss, Analysis Support Seat of the Phelan-McDermid Base. This will be the first scientific trial in Phelan-McDermid Syndrome to emerge from convincing preclinical proof in a model system. The cause of autism offers been debated for many years. Currently the best scientific evidence signifies that genetic mutations are the most most likely culprits, acting either straight or indirectly, in up to 80 to 90 % of individuals with ASDs.